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In vitro and animal-based studies have explored AOD-9604's interactions with osteoblast and osteoclast activity, investigating its role in bone remodeling pathways independent of IGF-1 signaling

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Similarly, corticosteroids should be used with great caution in patients with Strongyloides hyperinfection and dissemination with widespread larval migration, often accompanied by severe enterocolitis and potentially fatal Gram- sepsis

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